Diagnosis 9 – Estrogen Metabolism towards 16OH (bad!)
May 15, 2010
Turned out that Nanay is metabolizing estrogen towards the 16OH pathway (the bad estrogen metabolite). So her Doctor prescribed a special formula of I3C, DIM, Cat’s Claw, Reservatol and a few other herbs (to support her liver and kidney). All these herbs/supplements in 1 single capsule. He also gave my mother another form of Calcium ( from Calcium D-Glucarate).
The doctor said, the idea is not to remove estrogen at all (as u said we need estrogen), but to support the liver/kidneys so that estrogen is metabolized towards the better metabolite (2OH) rather than 16OH.
– have been named “good estrogen” and thought to be cancer protective.
– have been named the “bad estrogen” and thought to be the agressive type of estrogen and is carcinogenic.
In this test, what we are really looking for is the ratio of 2OH to 16OH metabolite.
A reatio of 2OH to 116OH greater than 2.0 is desirable.
A ratio less than 2.0 may increase the risk of cancer (or cancer recurrence)
Nanay’s rest results showed that her 2/16 OH ratio is 0.55 which is way below 2.0 (desirable)
2 OH (protective) =2.09 (Range 0.09-5.82 ug/gCR)
16 OH (proliferative) = 3.77 (range 0.06-5.00 ug/gCR)
2/16 OH Ratio = 0.55 (Range 0.50 – 8.00 ug/gCR)